Kyzatrex Capsule: Uses, Dosage, Side Effects, Precautions and Alternates

Quick overview

Kyzatrex Capsule contains testosterone undecanoate, an oral form of testosterone, and belongs to the androgens and anabolic steroids drug class. It is a prescription medicine used in adult men with low or no testosterone caused by certain medical conditions, such as problems with the testicles, pituitary gland, or hypothalamus. It is not used for age-related low testosterone and is not approved for women or children under 18.

What is Kyzatrex Capsule

Kyzatrex is a liquid-filled capsule containing testosterone undecanoate. It is a prescription medicine used to treat adult men who have low or no testosterone caused by certain medical conditions, such as problems with the testicles, pituitary gland, or hypothalamus.

Kyzatrex Capsule uses

• Treats low testosterone in men caused by hypogonadism, including problems with the testicles, pituitary gland, or hypothalamus
• Testosterone replacement therapy in adult males for conditions causing a deficiency or absence of the body's own testosterone
• Not used to treat low testosterone that is simply due to aging ("age-related hypogonadism")
• Not approved for use in women or in children younger than 18 years old

Benefits of Kyzatrex Capsule

• Improved mood and energy
• Improved muscle mass
• Better bone mineral density
• Increased sex drive and overall sexual function
• Better erectile function
• Steady hormone levels
• Convenient, non-invasive way to take testosterone (no needles)

How Kyzatrex Capsule works

Testosterone is a hormone the body makes naturally that supports growth and function of male sexual organs and other male characteristics. Kyzatrex works by replacing this testosterone. Low testosterone can happen when the testicles themselves are not working properly, or when the pituitary gland or hypothalamus in the brain does not signal the testicles correctly.

Kyzatrex Capsule dosage

Take by mouth with food, usually twice a day: once in the morning and once in the evening. If your dose only calls for one dose per day, take it in the morning. Take it around the same time every day to help keep steady testosterone levels. Some brands should not be chewed and should be swallowed whole for the best effect — follow your doctor's specific directions. Do not change your dose or how often you take it without talking to your doctor first.

Your doctor will need to do regular blood tests to check your testosterone levels and may adjust your dose based on results. Your blood pressure will need to be checked regularly while you take this medicine. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for your next dose — do not take two doses at once. Do not keep leftover medicine; dispose of unused capsules through a medicine take-back program.

Available forms and strengths

Capsules (liquid-filled), available in 50 mg, 100 mg, 150 mg, and 200 mg strengths.

Side effects of Kyzatrex Capsule

Common

• Increased red blood cell counts
• Enlarged prostate
• More frequent or longer-lasting erections
• Increased blood pressure
• Nausea, heartburn, burping
• Diarrhea
• Headache
• Swelling in lower legs
• Joint, muscle, or back pain
• Cold symptoms
• Breast swelling or tenderness
• Weight gain
• Oily skin, hair loss, acne
• Changes in sexual interest

Serious

• Signs of an allergic reaction: hives, difficulty breathing, swelling of face, lips, tongue, or throat
• Increased blood pressure that can raise the risk of heart attack, stroke, or death
• Breast pain or swelling
• Sleep apnea (breathing stops during sleep)
• Unusual mood or behavior changes, new or worsening depression, suicidal thoughts or actions
• Heart problems: swelling, rapid weight gain, feeling short of breath
• Liver problems: loss of appetite, stomach pain, tiredness, itching, dark urine, clay-colored stools, yellowing of skin or eyes
• Signs of a blood clot in the lung: chest pain, sudden cough or shortness of breath, wheezing, rapid breathing, coughing up blood
• Signs of a blood clot in the leg: pain, swelling, or warmth
• Signs of an enlarged prostate: increased urination, weak urine stream, urgent need to urinate, loss of bladder control
• Painful or prolonged erection lasting 4 or more hours
• Increased red blood cell count, which can raise risk of blood clots, stroke, and heart attack
• Increased risk of prostate cancer

Warnings and precautions

• Kyzatrex can raise blood pressure, which over time can raise the risk of serious heart and blood vessel problems like heart attack and stroke. Your blood pressure should be checked regularly.
• Do not take Kyzatrex if you have known or suspected prostate cancer, breast cancer, or if you are a woman who is pregnant.
• Kyzatrex can increase red blood cell counts, which raises the risk of blood clots, strokes, and heart attacks. Your doctor should check your blood counts regularly while you take this medicine.
• Blood clots can form in the legs or lungs while using this medicine.
• If you have an enlarged prostate, Kyzatrex may make your symptoms worse, and testosterone use may increase the risk of prostate cancer. Your doctor should check your prostate before and during treatment.
• Kyzatrex can worsen sleep apnea, especially in people who are overweight or have chronic lung disease.
• Kyzatrex can cause swelling (edema), with or without heart failure, especially in people with existing heart, kidney, or liver disease.
• Kyzatrex can cause breast enlargement or tenderness (gynecomastia) that may not go away.
• Large doses of testosterone can reduce sperm count and may affect fertility, sometimes permanently.
• Just one dose of this medicine can be deadly if taken accidentally or improperly by someone it wasn't prescribed for. Keep it stored safely away from others, and never share it — sharing or selling this medicine is against the law.
• Testosterone can be misused or abused, which may lead to addiction, serious heart problems, or psychiatric problems like depression, aggression, or psychosis.
• In children, improper use may affect bone growth, so this medicine is not recommended for those under 18.
• Kyzatrex must not be used by women who are pregnant, as it can cause serious harm to an unborn baby. Kyzatrex is not meant for use in women, so it is not indicated for breastfeeding either.
• Tell your doctor if you have kidney problems before taking Kyzatrex, since fluid retention and swelling can be a serious problem in patients with existing kidney disease.
• Tell your doctor if you have liver problems before taking Kyzatrex. Watch for signs of liver trouble like yellowing skin or eyes, dark urine, or stomach pain, and tell your doctor right away if these occur.
• Testing found that Kyzatrex's absorption was not affected when taken with alcohol along with a high-fat meal, compared to a high-fat meal alone.

Storage

• Store at room temperature between 68°F to 77°F (20°C to 25°C)
• Store in a dry place, away from moisture and heat
• Do not store in the bathroom
• Keep out of the reach of children and pets
• Throw away unused medicine through a take-back option; if one is not available, follow FDA instructions for safely disposing of medicine
• Do not flush medication down the toilet or pour it into a drain unless instructed to do so

When to see a doctor

• Get emergency medical help right away if you have signs of a severe allergic reaction, such as hives, trouble breathing, or swelling of your face, lips, tongue, or throat.
• Get medical help right away if you have chest pain, shortness of breath, rapid breathing, sudden dizziness or fainting, confusion, unusual sweating, sudden severe headache, trouble speaking, weakness on one side of the body, or sudden vision changes — these can be signs of a heart attack, stroke, or blood clot.
• If you have a painful erection that lasts 4 or more hours, stop using this medicine and get medical help right away to avoid permanent damage.
• Call your doctor right away if you notice pain or swelling in your breasts, signs of sleep apnea, mood or behavior changes, symptoms of heart problems (swelling, rapid weight gain, shortness of breath), signs of liver problems, or signs of an enlarged prostate.
• If you suspect an overdose and have serious symptoms such as passing out or trouble breathing, seek emergency medical attention immediately.

Alternatives

• AndroGel
• Xyosted
• Jatenzo
• Depo-Testosterone
• Methyltestosterone
• Tlando