Safety
General information, not medical advice
Your prescriber and the leaflet in your pack know your situation. This page does not.
- Follow your prescriber and the leaflet
- Don't start, stop, or change a dose on your own
- Doses and warnings differ by country and product
Zosert Tablet: Uses, Dosage, Side Effects, Precautions and Alternates
| Generic name | Sertraline |
|---|---|
| Drug class | Selective serotonin reuptake inhibitor (SSRI) |
| Forms | Tablet, Capsule, Oral suspension |
Quick overview
Zosert Tablet contains sertraline, a medicine from the selective serotonin reuptake inhibitor (SSRI) group. It is used to treat depression, panic disorder, social anxiety disorder, post-traumatic stress disorder, obsessive-compulsive disorder, and premenstrual dysphoric disorder. It works by balancing serotonin levels in the brain. It is available as a tablet, capsule, and oral suspension.
What is Zosert Tablet
Zosert is an antidepressant medicine that contains sertraline, which belongs to the selective serotonin reuptake inhibitor (SSRI) group of medicines. It is used to treat several mental health conditions by helping to balance serotonin levels in the brain.
Zosert Tablet uses
- Depression and prevention of repeat episodes of depression
- Panic disorder
- Social anxiety disorder
- Post-traumatic stress disorder (PTSD)
- Obsessive-compulsive disorder (OCD), including in children and teenagers aged 6-17 years
- Premenstrual dysphoric disorder (PMDD)
Benefits of Zosert Tablet
- Reduces sadness, hopelessness, and feelings of emptiness linked to depression
- Helps regain interest in daily activities, improve relationships, and improve focus at work or school
- Improves sleep patterns
- Reduces excessive worry, nervousness, and anxious thoughts
- Helps patients feel calmer and more in control
- Reduces frequency and severity of panic attacks
How Zosert Tablet works
Zosert works by increasing the level of serotonin, a chemical messenger in the brain that affects mood. This helps improve mood, reduce anxiety, promote better sleep, and improve emotional stability, and also helps reduce panic attacks and unwanted thoughts.
Zosert Tablet dosage
Zosert can be taken with or without food, as directed by your doctor. If you feel nauseous, taking it with food may help. Swallow the tablet whole with a glass of water; do not crush or chew it. Take the medicine at the same time every day, preferably in the morning or evening, to help it work best. If you have trouble sleeping, your doctor may suggest taking it in the morning.
It may take a few weeks to notice an improvement in symptoms, so tell your doctor if you don't feel better after some weeks. Keep taking the medicine even if you feel better; do not stop or change the dose without talking to your doctor, as this may worsen your condition or cause withdrawal symptoms.
If you forget a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed one and continue your normal schedule. Do not take an extra dose to make up for a missed one.
| Age group | Dose |
|---|---|
| Under 18 Years | Use only if prescribed by a healthcare professional |
| Adults (18–64 Years) | 25–50 mg once daily, adjusted according to condition |
| Older Adults (65+ Years) | 25–50 mg once daily, adjusted based on response and health condition |
Available forms and strengths
- Tablet
- Capsule
- Oral suspension
Side effects of Zosert Tablet
Common
- Nausea
- Dizziness
- Dry mouth
- Fatigue
- Increased sweating
- Loss of appetite
- Insomnia (trouble sleeping)
- Diarrhea
- Headache
- Sexual problems, including delayed ejaculation and reduced sex drive
- Tremors
- Changes in taste
- Indigestion
Serious
- Signs of low sodium levels, such as nausea, vomiting, headache, and confusion
- Itchy skin rash, breathing problems, wheezing, or swelling of the eyelids, face, or lips (signs of an allergic reaction)
- Severe skin rash with blisters on the mouth and tongue (signs of a rare but serious skin reaction)
- Signs of serotonin syndrome, such as agitation, confusion, high temperature and blood pressure, diarrhea, excessive sweating, and rapid heartbeat
- Yellow skin and eyes, which may mean liver damage
Warnings and precautions
- Do not take this medicine if you are allergic to sertraline or any other ingredient in it.
- This medicine should not be used if you have angle closure glaucoma.
- Should not be taken together with MAO inhibitor medicines, as this combination can be dangerous; wait at least two weeks after stopping an MAOI before starting this medicine.
- Can increase the risk of suicidal thoughts and behavior changes; caregivers should watch for warning signs and tell the doctor right away if they notice anything unusual.
- Can cause low sodium levels in the blood, especially in elderly people or those taking certain water pills; your doctor may check your blood levels during treatment.
- Should be used carefully if you have a history of seizures, as it may increase the chance of a seizure happening.
- Do not stop this medicine suddenly, since this can cause withdrawal symptoms like dizziness, sleep problems, tremor, and anxiety; talk to your doctor before stopping.
- Not recommended for children younger than six years old.
- Avoid drinking grapefruit juice while taking this medicine, since it may raise the amount of the medicine in your body.
- Use with caution and only if clearly necessary, and only after talking with your doctor, since animal studies have shown possible effects on the growing baby.
- Use with caution and talk to your doctor first, as the medicine can pass into breast milk in small amounts.
- Use with caution if you have mild, moderate, or severe kidney problems; your dose may need to be adjusted.
- Not usually recommended for people with liver problems, and should be used carefully in people with other liver diseases; the dose may need to be adjusted.
- Avoid drinking alcohol while taking this medicine, as it can increase side effects like dizziness and drowsiness.
- Do not drive or use machines if the medicine makes you feel dizzy or drowsy, since it can affect your ability to do so safely.
Storage
- Store Zosert 50 Tablet in a cool, dry place away from direct sunlight.
- Protect it from light and moisture.
- Keep it out of reach and sight of children.
- Use the medicine before the expiration date mentioned on the packaging.
- Store Below 30° C
When to see a doctor
- Get medical help right away if you notice signs of low sodium levels like nausea, vomiting, headache, and confusion.
- Seek urgent care for signs of an allergic reaction, such as an itchy rash, breathing trouble, wheezing, or swelling of the eyelids, face, or lips.
- Get emergency help for a severe skin reaction with rash and blisters on the mouth and tongue.
- Seek immediate medical attention for signs of serotonin syndrome, including agitation, confusion, high temperature and blood pressure, diarrhea, excessive sweating, and rapid heartbeat.
- Tell your doctor right away if you notice yellowing of the skin or eyes, which could mean liver damage.
- Seek help immediately if you have thoughts of harming or killing yourself.
- Contact your doctor if you feel restless and unable to sit or stand still.
- Get medical help if you have a seizure while taking this medicine.
- Tell your doctor if you have symptoms of a manic episode.
- If you take too much of this medicine, seek emergency medical attention immediately and bring the medicine strip or bottle with you.
Alternatives
- Escitalopram
- Paroxetine
- Bupropion
Watch the video
FAQs
What is Zosert Tablet used for?
Zosert Tablet is used to treat depression, panic disorder, social anxiety disorder, post-traumatic stress disorder, obsessive-compulsive disorder (including in children aged 6-17 years), and premenstrual dysphoric disorder.
How does Zosert Tablet work?
Zosert works by increasing the level of serotonin, a chemical messenger in the brain that affects mood, helping improve mood, reduce anxiety, promote better sleep, and reduce panic attacks and unwanted thoughts.
What are the common side effects of Zosert Tablet?
Common side effects include nausea, dizziness, dry mouth, fatigue, increased sweating, loss of appetite, insomnia, diarrhea, headache, sexual problems, tremors, changes in taste, and indigestion.
What is the dosage of Zosert Tablet for adults?
Adults aged 18-64 years are typically given 25-50 mg once daily, adjusted according to their condition, while older adults receive the same dose adjusted based on response and health condition.
Can I drink alcohol or grapefruit juice while taking Zosert Tablet?
Alcohol should be avoided as it can increase side effects like dizziness and drowsiness, and grapefruit juice should also be avoided since it may raise the amount of medicine in your body.
General information, not medical advice
Your prescriber and the leaflet in your pack know your situation. This page does not.
- Follow your prescriber and the leaflet
- Don't start, stop, or change a dose on your own
- Doses and warnings differ by country and product
Sources
- K.D. Tripathi, Drugs Used in Mental Illness: Antidepressant and Antianxiety Drugs. Essentials of medical pharmacology. Seventh edition. 2013 Page 461.
- Andrea Cipriani, Teresa La Ferla, Toshi A Furukawa, Alessandra Signoretti, Atsuo Nakagawa, Rachel Churchill, Hugh McGuire, and Corrado Barbui. Sertraline versus other antidepressive agents for depression. NIH National Library of Medicine.
- Almatica Pharma LLC. Food and Drug Administration (FDA).
- ZENTIVA k. s. Electronic Medicines Compendium (EMC).
- Haupt Pharma Latina S.r.l. Electronic Medicines Compendium (EMC).
- Medicines.org.uk. Sertraline 100mg film-coated Tablets - Summary of Product Characteristics (SmPC).
- MedlinePlus Drug Information - Sertraline.
- DailyMed - SERTRALINE- sertraline hydrochloride tablet, film coated.
- TGA eBS - Product and Consumer Medicine Information.
- Zoloft (2016). Sertraline Hydrochloride label.
- Stahl, S.M. (2014). Sertraline. In: Stahl's Essential Psychopharmacology: Prescriber's Guide. 5th ed.
- Chaves, R.G. and Lamounier, J.A. (2004). Breastfeeding and maternal medications. J Pediatr (Rio J), 80(5 Suppl), S189-S198.
- Central Drugs Standard Control Organisation (CDSCO).
Video
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