Aceclofenac Tablet: Uses, Dosage, Side Effects, Precautions and Alternates

Quick overview

Aceclofenac Tablet contains Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID) that acts as a preferential COX-2 inhibitor. It is used to relieve pain, inflammation, and fever, often affecting the bones and joints. It works by blocking the COX enzyme, which lowers the chemicals responsible for pain, swelling, and inflammation.

What is Aceclofenac Tablet

Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID). It is used to relieve pain and inflammation, often in the bones and joints. It works by blocking the COX enzyme, which lowers the chemicals that cause pain, swelling, and inflammation.

Aceclofenac Tablet uses

• Relief of pain and stiffness in rheumatoid arthritis
• Relief of pain and stiffness in ankylosing spondylitis
• Relief of tender, painful joints in osteoarthritis
• Relief of fever, pain, and inflammation
• Relief of gout
• Relief of general body pains linked to physical stress
• Relief of post-operative pain
• Relief of menstrual cramps
• Relief of migraine headache
• Relief of toothache
• Relief of low back pain
• Relief of frozen shoulder (scapulohumeral periarthritis)

Benefits of Aceclofenac Tablet

• Helps relieve pain and reduce inflammation
• Helps reduce swelling and stiffness of the joints
• Helps lower fever
• Helps protect joints in osteoarthritis by preventing the breakdown of cartilage

How Aceclofenac Tablet works

Aceclofenac blocks the COX enzyme (mainly COX-2). This enzyme makes chemicals called prostaglandins at the site of an injury, which cause swelling, pain, and inflammation. By blocking COX, aceclofenac lowers prostaglandins and helps relieve pain and reduce inflammation.

Aceclofenac Tablet dosage

Take the tablet by mouth and swallow it whole with a glass of water. Do not crush or chew the tablet. Take it during or after a meal, or with milk, to help avoid stomach irritation or indigestion. Do not take it on an empty stomach. Follow the prescribed dosage and do not take more than prescribed. It is not recommended for children under 18 years of age due to a lack of clinical evidence.

Available forms and strengths

• Film-coated tablet (100 mg)
• Extended release tablet (200 mg)

Side effects of Aceclofenac Tablet

Common

• Nausea
• Vomiting
• Diarrhoea
• Abdominal pain
• Indigestion (dyspepsia)
• Flatulence
• Constipation
• Heartburn
• Loss of appetite
• Skin rashes
• Dizziness
• Blurry vision (visual disturbance)
• Raised liver enzymes

Serious

• Gastrointestinal bleeding
• Hypersensitivity reactions such as hives (urticaria)
• Angioedema (swelling of the lips, tongue, or throat)
• Shortness of breath (dyspnea)
• Anaemia
• Low platelet count (thrombocytopenia)
• Hepatitis (inflammation of the liver)
• Low white blood cell counts (granulocytopenia, neutropenia)
• Depression
• Swelling (oedema)

Warnings and precautions

• Aceclofenac should be avoided in pregnancy unless the benefit clearly outweighs the risk to the baby. Use in the last trimester is not advised. Tell your doctor if you are pregnant or planning to become pregnant.
• There is no evidence that aceclofenac passes into breast milk, but it is not recommended during breastfeeding. Tell your doctor if you are breastfeeding.
• Use with caution if you have kidney problems. It is not preferred in severe kidney disease. Kidney function should be monitored, and the lowest effective dose is preferred.
• Use with caution if you have liver problems. It is not preferred in liver failure. Liver function should be monitored closely and the dose may need to be lowered.
• Aceclofenac can cause drowsiness, dizziness, visual disturbances, vertigo, and fatigue. If you have any of these effects, do not drive or use machines.
• Do not take aceclofenac if you have had an allergic reaction to an NSAID such as diclofenac, naproxen, or aspirin.
• Do not use aceclofenac if you have active or a history of stomach ulcers or intestinal bleeding.
• Do not use aceclofenac if you have severe kidney disease, liver failure, heart attack, or cerebrovascular disease.
• Gastrointestinal bleeding, ulceration, or perforation can be fatal and can happen with or without warning symptoms during treatment.
• Aceclofenac is contraindicated in people with congestive heart failure.
• Use with caution if you have asthma or another allergic disorder because of the risk of bronchospasm.
• Do not take aceclofenac with other medicines unless your doctor tells you to. Blood thinners such as acenocoumarol, warfarin, and strontium may interact with it.

Storage

• Store the tablets below 30 °C and protect from sunlight.
• Store in a dry and cool place, away from light and direct heat.
• Keep all medicines out of the sight and reach of children.
• Do not use the medicine after the expiration date and do not use expired medicine.

When to see a doctor

• If you have any of the side effects again and again, stop taking the medicine and contact your doctor right away.
• If you or someone else takes too much aceclofenac, go to the emergency department of the nearest hospital straight away and take the medicine container with you. An overdose can badly damage the kidney, liver, or other organs.
• Seek medical attention if you have severe side effects such as gastrointestinal bleeding or an allergic reaction.

Alternatives

• Diclofenac
• Ibuprofen
• Naproxen
• Meloxicam
• Celecoxib
• Etoricoxib
• Ketoprofen