Combiflam Tablet: Uses, Dosage, Side Effects, Precautions and Alternates

Quick overview

Combiflam Tablet is a prescription medicine that combines ibuprofen (400 mg) and paracetamol (325 mg), two pain relievers belonging to the NSAID, analgesic, and antipyretic drug class. It is used to relieve mild to moderate pain and reduce fever. The two ingredients work through different mechanisms to ease pain, swelling, and high temperature.

What is Combiflam Tablet

Combiflam Tablet is a prescription medicine that combines two pain relievers, ibuprofen and paracetamol. It is used to relieve mild to moderate pain and reduce fever. It works through different mechanisms to ease pain, swelling, and high temperature.

Combiflam Tablet uses

• Mild to moderate pain such as headaches, toothaches, muscle pain, sprains, strains, and back pain
• Joint pain and inflammation from conditions like osteoarthritis, rheumatoid arthritis, and gout
• Menstrual cramps and period pain
• Fever, including fever linked to cold, flu, and other infections
• Short-term pain relief after dental or medical procedures

Benefits of Combiflam Tablet

• Provides effective relief from pain by working through more than one pathway
• Helps lower fever and relieve related symptoms such as chills and body aches
• May help you carry out daily activities more comfortably by reducing pain
• Combines two commonly used pain relievers in a single tablet

How Combiflam Tablet works

Combiflam contains ibuprofen and paracetamol. Paracetamol acts mainly in the central nervous system to reduce pain perception and lower fever. Ibuprofen blocks COX enzymes, reducing the production of prostaglandins that cause pain, swelling, and inflammation. Together they help relieve pain and reduce fever.

Combiflam Tablet dosage

Take the tablet exactly as prescribed by your doctor. Swallow the tablet whole with a full glass of water; do not chew or crush it unless your doctor advises otherwise. Take this medicine with food or milk to help reduce stomach irritation. Take the medicine at the first sign of pain for best relief. Do not exceed the prescribed dose or recommended duration of treatment. Avoid taking other medicines containing paracetamol or ibuprofen unless advised by your doctor. Do not stop using this medicine without consulting your doctor.

Available forms and strengths

• Combiflam is available as a tablet, containing ibuprofen 400 mg and paracetamol 325 mg.

Side effects of Combiflam Tablet

Common

• Nausea or vomiting
• Stomach pain or discomfort
• Heartburn
• Indigestion
• Loose or watery stools (diarrhoea)
• Constipation
• Dizziness
• Drowsiness
• Fatigue
• Skin rash
• Loss of appetite

Serious

• Gastric or mouth ulcers
• Vomiting of blood
• Bloody and cloudy urine
• Abnormal blood counts
• Decreased urine output
• Yellow colored eyes or skin
• Ringing or buzzing in the ears
• Abnormal liver function test
• Severe skin reactions

Warnings and precautions

• Combiflam is not recommended during pregnancy unless clearly needed, and taking it in the last 3 months may harm the unborn baby. Talk to your doctor before using it.
• If you are breastfeeding, take Combiflam only if your doctor prescribes it. Discuss the risks and benefits with your doctor.
• Use Combiflam with caution if you have a history of kidney disease. Your doctor may need to adjust your dose.
• Use Combiflam with caution if you have a history of liver disease. It is not recommended for severe liver disease, and your doctor may need to adjust your dose.
• Avoid or limit alcohol while taking Combiflam, as it may cause dizziness or drowsiness and can damage your liver or increase the risk of stomach bleeding if used for a long time.
• After taking Combiflam you may feel dizzy, sleepy, drowsy, or tired. Avoid driving or operating machinery until you know how it affects you.
• Many cold, flu, and pain medicines contain paracetamol or NSAIDs. Check other medicines carefully to avoid taking the same ingredient twice.
• Do not exceed the recommended dose, as taking more may increase the risk of serious liver, kidney, or stomach problems.
• This medicine may cause severe gastrointestinal bleeding and perforation with prolonged use, which can happen with or without warning symptoms. The risk is higher in elderly people and those with a history of stomach problems.
• This medicine should be avoided in heart patients as it can lead to serious cardiovascular risks.
• This medicine is not recommended for people who drink alcohol regularly due to the increased risk of severe liver damage.
• Do not use if you are allergic to ibuprofen, paracetamol, or other NSAIDs. Allergic reactions may include swelling of the face, mouth and throat, difficulty breathing, itching or rash.
• This medicine is not suitable for children under a certain weight or age and may cause kidney problems in children and adolescents who are dehydrated.

Storage

• Store at controlled room temperature, ideally below 30°C.
• Keep the tablets in their original packaging to protect them from moisture and light.
• Keep the medicine out of reach of children.
• Always check the expiry date before use.

When to see a doctor

• Seek medical attention if you develop severe stomach pain, vomiting blood, black stools, difficulty breathing, severe skin reactions, or signs of liver problems.
• Get medical advice if you notice unusual bruising, prolonged bleeding, black stools, or blood in vomit.
• If you suspect you have taken an overdose, consult a doctor immediately.
• Report signs such as rashes, hives, fever, or other allergic symptoms to your doctor without any delay, as this medicine may cause serious skin allergies.

Alternatives

• Ibunija Kid Tablet
• Brufamol Tablet
• Zupar Tablet