Safety
General information, not medical advice
Your prescriber and the leaflet in your pack know your situation. This page does not.
- Follow your prescriber and the leaflet
- Don't start, stop, or change a dose on your own
- Doses and warnings differ by country and product
Concor Plus Tablet: Uses, Dosage, Side Effects, Precautions and Alternates
| Generic name | Bisoprolol + Hydrochlorothiazide |
|---|---|
| Drug class | Beta-blocker and thiazide diuretic combination |
| Forms | Tablet |
Quick overview
Concor Plus Tablet is a combination medicine containing bisoprolol and hydrochlorothiazide, a beta-blocker and thiazide diuretic combination. It is used to manage high blood pressure, especially when a single medicine is not enough to control it. By working together, the two medicines help control blood pressure, regulate heart rate, and reduce excess fluid in the body.
What is Concor Plus Tablet
Concor Plus Tablet is a combination medicine containing bisoprolol and hydrochlorothiazide, used to manage high blood pressure, especially when a single medicine is not enough to control it.
Concor Plus Tablet uses
- High blood pressure (hypertension), especially when one medicine alone isn't effective enough
- Helps prevent major cardiovascular events such as heart attacks and strokes
Benefits of Concor Plus Tablet
- Blood Pressure Control: Helps reduce high blood pressure.
- Heart Rate Control: Bisoprolol helps slow and regulate heart rate.
- Fluid Reduction: Hydrochlorothiazide helps remove excess salt and water.
- Heart Protection: Helps reduce workload on the heart.
- Cardiovascular Support: Helps manage hypertension when combination therapy is needed.
How Concor Plus Tablet works
Concor Plus contains two medicines that work together. Bisoprolol slows the heart rate and reduces how hard the heart has to work, which lowers blood pressure. Hydrochlorothiazide is a diuretic that helps the body pass out extra water and salt through urine, and over time it also relaxes blood vessels, improving blood flow. Together they lower blood pressure more than either medicine alone.
Concor Plus Tablet dosage
Take the tablet by mouth, swallowing it whole with some liquid, usually with breakfast. Follow the instructions, dosage, and timing prescribed by your doctor thoroughly, and do not change the dosage on your own. Take it at the same time every day. Do not stop taking it suddenly without talking to your doctor first; it must be stopped gradually if needed. Maintain the diet recommended by your doctor and avoid activities your doctor has told you not to do.
| Age group | Dose |
|---|---|
| Under 18 Years | Use only if prescribed by a healthcare professional |
| Adults (18–64 Years) | 1 tablet once daily (strength based on blood pressure response) |
| Older Adults (65+ Years) | 1 tablet once daily; monitor blood pressure, kidney function, and electrolytes |
Available forms and strengths
- Tablet
Side effects of Concor Plus Tablet
Common
- Fatigue
- Dizziness
- Headache
- Nausea
- Constipation
- Diarrhoea
- Cold hands and feet
- Slow heart rate (bradycardia)
- Increased blood uric acid levels, which can sometimes lead to gout
- Altered blood lipid (cholesterol and triglyceride) levels
Serious
- Difficulty breathing
- Swelling of the face or limbs
- Sudden weight gain
- Chest tightness
- Fainting
Warnings and precautions
- Do not take this medicine if you are allergic to bisoprolol, hydrochlorothiazide, or any other ingredient in the tablet.
- Older adults, especially those over 70, should use this medicine only under medical supervision, as they may be more likely to experience side effects and may have other health problems or take other medicines.
- Use in children under 18 should only happen with a doctor's guidance, as caution is needed.
- This medicine can affect blood sugar control, so people with diabetes need to have their sugar levels checked closely.
- Do not stop taking this medicine suddenly without your doctor's advice, as this can be dangerous.
- This medicine should not be used during pregnancy. Talk to your doctor if you are pregnant or planning to become pregnant before taking it.
- This medicine should not be used while breastfeeding. Talk to your doctor about the risks and benefits.
- Use with caution if you have any kidney problems. Talk to your doctor before starting this medicine.
- Use with caution if you have mild to moderate liver problems; it is not recommended for people with severe liver disease. Talk to your doctor if you have liver problems, as this medicine may affect liver function.
- It is best to avoid alcohol while taking this medicine, as it may increase the risk of dizziness and low blood pressure.
- This medicine may cause dizziness, especially when you first start taking it or when your dose is increased. Be careful when driving or operating machinery.
Storage
- Store below 25°C
- Store at room temperature, ideally between 15-30°C
- Keep it in a dry place, shielded from light and moisture
- Ensure the storage area is out of reach of children
- Always use this medicine before the expiry date indicated on the packaging
When to see a doctor
- If you take too much of this medicine, you may feel dizzy, tired, and have a slow heartbeat. Tell your doctor right away if you think you have taken too much.
- If any side effect does not improve or gets worse, speak to your doctor.
Alternatives
- Bisoprolol Tablet
- Metoprolol
- Hydrochlorothiazide
Watch the video
FAQs
What is Concor Plus Tablet used for?
It is used to manage high blood pressure, especially when a single medicine isn't enough, and helps prevent major cardiovascular events such as heart attacks and strokes.
How does Concor Plus Tablet work?
Bisoprolol slows the heart rate and reduces the heart's workload, while hydrochlorothiazide removes excess salt and water and relaxes blood vessels, together lowering blood pressure more effectively.
What are the common side effects of Concor Plus Tablet?
Common side effects include fatigue, dizziness, headache, nausea, constipation, diarrhoea, cold hands and feet, slow heart rate, increased uric acid, and altered blood lipid levels.
Can I stop taking Concor Plus Tablet suddenly?
No, you should not stop taking it suddenly without your doctor's advice, as it must be stopped gradually if needed.
Is Concor Plus Tablet safe during pregnancy?
No, this medicine should not be used during pregnancy; talk to your doctor if you are pregnant or planning to become pregnant.
General information, not medical advice
Your prescriber and the leaflet in your pack know your situation. This page does not.
- Follow your prescriber and the leaflet
- Don't start, stop, or change a dose on your own
- Doses and warnings differ by country and product
Sources
- MedlinePlus. Bisoprolol.
- MedlinePlus. Hydrochlorothiazide.
- U.S. Food and Drug Administration. (2011). ZIAC (bisoprolol fumarate and hydrochlorothiazide) Tablets.
- ZEBETA (BISOPROLOL FUMARATE) TABLETS - bisoprolol fumarate tablet.
- Hydrochlorothiazide: Uses, interactions, mechanism of action | DrugBank Online.
- Bisoprolol: Uses, interactions, mechanism of action | DrugBank Online.
Video
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