Cordran Cream: Uses, Dosage, Side Effects, Precautions and Alternates

Quick overview

Cordran Cream is a topical corticosteroid medicine containing flurandrenolide. It is used to relieve inflammation and itching caused by corticosteroid-responsive skin conditions such as allergic reactions, eczema, and psoriasis. It works by reducing inflammation and itching and by narrowing blood vessels in the skin. It should be used exactly as directed by a doctor, with care taken to avoid the eyes and to limit use on the face, underarms, and groin.

What is Cordran Cream

Cordran Cream is a topical corticosteroid medicine for the skin. It is used to treat inflammation and itching caused by certain skin conditions such as allergic reactions, eczema, and psoriasis.

Cordran Cream uses

• Relief of inflammation and itching caused by corticosteroid-responsive skin conditions (dermatoses)
• Allergic reactions
• Eczema
• Psoriasis

Benefits of Cordran Cream

• Reduces inflammation and swelling of the skin
• Relieves itching
• Helps calm skin irritation from corticosteroid-responsive conditions

How Cordran Cream works

Cordran works mainly by reducing inflammation, itching, and by narrowing blood vessels in the skin. Scientists believe it may help stabilize cell membranes so that certain enzymes that cause inflammation are not released, though the exact process is not fully understood.

Cordran Cream dosage

Use this medicine only as directed by your doctor, and only for the skin condition it was prescribed for. It is for external use on the skin only, and contact with the eyes should be avoided. For moist lesions, rub a small amount of the cream gently into the affected areas.

Do not cover or wrap the treated skin area (such as with a bandage) unless your doctor tells you to, since this can increase how much the medicine is absorbed. Do not use tight-fitting diapers or plastic pants over treated areas on infants or young children, since these can act like a covering that increases absorption. Do not use on the face, underarms, or groin unless your doctor tells you to, and do not use other corticosteroid products at the same time without checking with your doctor first.

If your skin does not improve after about two weeks, contact your physician. Stop using the cream once your skin condition is under control, as directed by your doctor. Do not use cosmetics or other skin care products on the treated areas.

Available forms and strengths

• Cream
• Ointment
• Lotion
• Tape

Side effects of Cordran Cream

Common

• Stinging
• Burning
• Itching
• Irritation
• Dryness
• Peeling or redness of the skin when first applied
• Skin rash or irritation around the mouth
• Redness or crusting around hair follicles
• Blisters
• Pimples
• Crusting of treated skin
• Stretch marks
• Increased hair growth
• Lightening of skin color
• Softening of skin

Serious

• Hives
• Difficulty breathing
• Swelling of face, lips, tongue, or throat
• Worsening of the skin condition being treated
• Redness, warmth, swelling, oozing, or severe irritation of treated skin
• Increased thirst or urination
• Dry mouth
• Fruity breath odor
• Weight gain, especially in the face, upper back, or torso
• Slow wound healing
• Thinning or discolored skin
• Muscle weakness
• Nausea
• Diarrhea
• Tiredness
• Mood changes
• Menstrual changes
• Sexual changes
• High blood sugar (hyperglycemia)
• Cushing's syndrome (a condition of high cortisol levels)
• Sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights
• Fast, irregular, or pounding heartbeat, fluttering in the chest, shortness of breath, sudden dizziness or fainting
• Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors

Warnings and precautions

• Using large amounts of this cream over a large area of skin, using it for a long time, or using it under a covering (occlusive dressing) can cause the body to absorb too much of it. This can affect hormone levels in the body and cause symptoms like high blood sugar or Cushing's syndrome.
• Children may absorb more of this medicine through their skin than adults, so they may be more at risk of side effects affecting the whole body. Long-term use of steroids like this in children can affect their growth and development. Children can absorb proportionally more corticosteroid and may have a higher risk of systemic effects, so the smallest amount necessary should be used.
• Do not use this medicine if you are allergic to flurandrenolide or any of the other ingredients in it. If your skin becomes irritated while using this cream, stop use and contact your doctor.
• If you have a skin infection, your doctor may need to treat the infection with another medicine, and this cream may need to be stopped until the infection is under control. If irritation develops, discontinue use and consult a healthcare professional. If a skin infection develops, appropriate antibacterial or antifungal treatment may be required; Cordran should be stopped if the infection does not improve promptly.
• For external use only. Avoid contact with the eyes. Do not apply to the face, underarms, or groin unless specifically directed by a doctor. Do not cover the treated area with tight bandages or occlusive dressings unless prescribed.
• Avoid using it on large areas or for prolonged periods because absorption can increase. Excessive or prolonged use may cause skin thinning, stretch marks, discoloration, folliculitis, and secondary infection. Systemic absorption may cause HPA-axis suppression, Cushing's syndrome, increased blood glucose, or glucose in the urine.
• This medicine should be used during pregnancy only if your doctor has prescribed it, since studies in pregnant women have not fully established the risks of topical corticosteroids on a developing baby.
• It is not known if using this cream on the skin leads to enough absorption to appear in breast milk. Caution should be used if you are breastfeeding, and you should talk to your doctor first.
• Once absorbed into the body, this type of medicine is processed mainly by the liver.

Storage

• Keep tightly closed.
• Protect from light.
• Store at 20° to 25°C (68° to 77°F) with excursions permitted to 15° to 30°C (59° to 86°F).
• Keep out of reach of children.

When to see a doctor

Get medical help right away if you notice hives, trouble breathing, or swelling of your face, lips, tongue, or throat. Seek medical care right away for serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights.

Seek medical care right away for serious heart symptoms such as a fast, irregular, or pounding heartbeat, fluttering in your chest, shortness of breath, or sudden dizziness, lightheadedness, or passing out. Seek medical care right away for a severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, heavy sweating, or tremors.

Talk to your doctor right away if you notice blurred vision, dizziness or fainting, a fast or irregular heartbeat, increased thirst or urination, irritability, or unusual tiredness or weakness, since these may signal a problem with your adrenal glands.

Alternatives

• Hydrocortisone butyrate 0.1%
• Mometasone furoate 0.1%
• Betamethasone valerate 0.1%