Safety

General information, not medical advice

Your prescriber and the leaflet in your pack know your situation. This page does not.

  • Follow your prescriber and the leaflet
  • Don't start, stop, or change a dose on your own
  • Doses and warnings differ by country and product
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CosmoCol Sachet: Uses, Dosage, Side Effects, Precautions and Alternates

· 4 min read

CosmoCol Sachet: Uses, Dosage, Side Effects, Precautions and Alternates
Generic nameMacrogol 3350 with electrolytes (sodium chloride, sodium hydrogen carbonate, potassium chloride)
Drug classOsmotic laxative
FormsPowder sachets for oral solution
CosmoCol Sachet: Uses, Dosage, Side Effects, Precautions and Alternates product

Quick overview

CosmoCol Sachet contains macrogol 3350 along with electrolytes (sodium chloride, sodium hydrogen carbonate, and potassium chloride) and belongs to the osmotic laxative class. It comes as a powder in sachets and is used to treat constipation and faecal impaction, a large build-up of stool that blocks the bowel. It works by drawing water into the bowel to soften stool and ease bowel movements, while its electrolytes help maintain the body's sodium and potassium balance.

What is CosmoCol Sachet

CosmoCol is a laxative that comes as a powder in sachets. It contains macrogol 3350 along with electrolytes (salts) and is used to treat constipation and faecal impaction, where a large build-up of stool blocks the bowel.

CosmoCol Sachet uses

  • Treats chronic constipation
  • Softens hard stools
  • Helps increase bowel-movement frequency
  • May be used for faecal impaction under appropriate medical guidance

Benefits of CosmoCol Sachet

  • Draws water into the bowel to soften stool
  • Generally suitable for longer-term constipation management when advised
  • Contains electrolytes to help limit major electrolyte shifts
  • Available in adult and pediatric sachet formulations

How CosmoCol Sachet works

Macrogol holds water in the bowel, which makes stools bigger and softer and increases movement in the gut, triggering a bowel movement. The electrolytes in CosmoCol help keep your body's sodium and potassium levels balanced while the laxative works.

CosmoCol Sachet dosage

Dissolve each sachet fully in the correct amount of water before drinking, and drink the mixed solution right away. Do not use starch-based thickeners with CosmoCol, as this can make the liquid unsafe to swallow. The water used to mix the sachet is not absorbed into the body and should not be counted as part of your daily fluid intake. Stop taking it once you have passed a large amount of stool, which usually happens within a few days of starting treatment.

Treatment for chronic constipation is not usually continued for more than two weeks unless your doctor tells you to. CosmoCol is not usually recommended for children under 12 years of age unless a healthcare professional advises otherwise. Speak to your doctor or pharmacist before use if you are taking other medicines, as some may need to be taken at a different time from CosmoCol.

Age groupDose
Under 2 yearsNo standard dose for the regular CosmoCol sachet; medical advice is required
2–6 yearsWith CosmoCol Paediatric 6.9 g: usually 1 sachet once daily initially
7–11 yearsWith CosmoCol Paediatric 6.9 g: usually 2 sachets daily initially
12–17 yearsWith standard CosmoCol 13.8 g: 1 sachet 1–3 times daily

Available forms and strengths

  • Powder sachets for oral solution

Side effects of CosmoCol Sachet

Common

  • Abdominal pain or stomach pain
  • Bloating or abdominal distension
  • Flatulence (wind)
  • Stomach rumbling (borborygmi)
  • Feeling sick (nausea)
  • Being sick (vomiting)
  • Mild diarrhoea or loose stools
  • Anal discomfort or a sore bottom

Serious

  • Allergic reactions, including anaphylaxis, with symptoms such as rash, itching, shortness of breath, or difficulty breathing
  • Signs of fluid or electrolyte imbalance, such as swelling (especially in the ankles), feeling weak or increasingly tired, feeling thirsty with a headache, or shortness of breath

Warnings and precautions

  • Do not use CosmoCol if you have a blockage or perforation in the gut, severe inflammatory bowel conditions such as ulcerative colitis, Crohn's disease, or toxic megacolon, or if you are allergic to any of its ingredients.
  • Your doctor should confirm a diagnosis of faecal impaction before you start high-dose treatment, and extra care is needed if you have problems with your gag reflex, acid reflux, or reduced consciousness.
  • CosmoCol must not be mixed with starch-based thickeners, as this can make the liquid unsafe to swallow.
  • The lemon and lime flavour contains sorbitol, so people with a rare hereditary fructose intolerance should not take this version.
  • CosmoCol can reduce how well some other medicines are absorbed, including anti-epileptic drugs, so tell your doctor or pharmacist about any other medicines you take.
  • There isn't enough information on using CosmoCol during pregnancy, so it should only be used if your doctor thinks it's necessary. Talk to your doctor or pharmacist before taking it if you're pregnant.
  • There isn't enough information on using CosmoCol while breastfeeding, so it should only be used if your doctor thinks it's necessary.
  • Each sachet contains sodium and potassium, so kidney disease or a restricted sodium/potassium diet requires medical advice.
  • No routine liver-specific dose adjustment is generally required.
  • No major direct interaction with alcohol is established, but maintaining good hydration is important.
  • CosmoCol does not affect your ability to drive or use machines.

Storage

  • Store in a cool, dry place below 25 degrees C
  • Do not use this product if the expiry date printed on the original packaging has passed
  • Keep out of sight and reach of children
  • Reconstituted CosmoCol solution can be covered and stored in the refrigerator (2°C to 8°C), and should be used within 24 hours. After 24 hours, any unused solution should be discarded.

When to see a doctor

  • Stop taking CosmoCol and see your doctor right away if you notice signs of a fluid or salt imbalance, such as swelling, shortness of breath, increasing tiredness, dehydration, or heart problems.
  • Stop use and get immediate medical help if you have signs of an allergic reaction, such as rash, itching, or difficulty breathing.

Alternatives

  • Movicol
  • Laxido
  • Lactulose

Watch the video

Video: CosmoCol Sachet: Uses, Dosage, Side Effects, Precautions and Alternates

FAQs

What is CosmoCol Sachet used for?

CosmoCol Sachet is used to treat chronic constipation and faecal impaction, a large build-up of stool that blocks the bowel, by softening stool and increasing bowel-movement frequency.

How does CosmoCol Sachet work?

Macrogol in CosmoCol holds water in the bowel, making stools bigger and softer and increasing gut movement to trigger a bowel movement, while its electrolytes help keep sodium and potassium levels balanced.

How long can I take CosmoCol Sachet?

Treatment for chronic constipation is not usually continued for more than two weeks unless your doctor advises otherwise, and you should stop once you have passed a large amount of stool, usually within a few days.

Can I mix CosmoCol Sachet with starch-based thickeners?

No, CosmoCol must not be mixed with starch-based thickeners, as this can make the liquid unsafe to swallow.

What are the common side effects of CosmoCol Sachet?

Common side effects include abdominal pain, bloating, flatulence, stomach rumbling, nausea, vomiting, mild diarrhoea, and anal discomfort.

General information, not medical advice

Your prescriber and the leaflet in your pack know your situation. This page does not.

  • Follow your prescriber and the leaflet
  • Don't start, stop, or change a dose on your own
  • Doses and warnings differ by country and product
Facts checked by a personSourcesFull disclaimer

Sources

  1. https://www.theindependentpharmacy.co.uk/constipation/cosmocol
  2. https://www.chemist-4-u.com/cosmocol-orange-flavour-sachets-pack-of-30
  3. https://www.stirlinganglianpharmaceuticals.com/products/cosmocol/