Depran Tablet: Uses, Dosage, Side Effects, Precautions and Alternates

Quick overview

Depran Tablet combines Escitalopram, an SSRI antidepressant, and Clonazepam, a benzodiazepine anti-anxiety drug. It is a prescription medicine used to treat depression and anxiety disorders that occur together. Depran helps reduce panic attacks, relieves persistent worry and nervous tension, and works by balancing brain chemicals that affect mood and nerve activity.

What is Depran Tablet

Depran is a prescription medicine that combines two active ingredients, Escitalopram (an SSRI antidepressant) and Clonazepam (a benzodiazepine anti-anxiety drug). It is used to treat depression and anxiety disorders together.

Depran Tablet uses

• Treats depression and anxiety disorders that occur together
• Helps reduce the frequency and severity of panic attacks
• Relieves persistent worry, nervousness, and physical tension from generalized anxiety disorder
• Calms the brain and reduces abnormal nerve cell activity
• Helps improve low mood by increasing serotonin levels in the brain

Benefits of Depran Tablet

• Treats clinical depression and anxiety at the same time
• Reduces panic attacks
• Eases persistent worry and nervous tension
• Helps you feel calmer and more relaxed

How Depran Tablet works

Escitalopram raises the level of serotonin, a brain chemical that helps balance mood, by blocking its reabsorption into nerve cells. Clonazepam boosts the activity of a calming brain chemical called GABA, which reduces excessive nerve activity and tension. Together, they help treat both depression and anxiety.

Depran Tablet dosage

Take this medicine exactly as instructed by your doctor. It can be taken with or without food, as advised by your doctor. Swallow the tablet with water; do not crush, chew, or break it. Follow the prescribed schedule strictly and do not miss doses.

If a dose is missed, take it as soon as possible, but skip it if it is almost time for the next dose; do not double the dose. Do not stop taking this medicine suddenly without talking to your doctor, as this can cause withdrawal symptoms.

This medicine is not recommended for use in children unless prescribed by a specialist. Older adults may be more sensitive to this medicine's effects and should be monitored by their doctor.

Available forms and strengths

• Tablet

Side effects of Depran Tablet

Common

• Drowsiness
• Fatigue
• Dizziness
• Confusion
• Dry mouth
• Nausea
• Constipation
• Memory impairment
• Decreased sexual desire
• Headache
• Diarrhea
• Decreased appetite
• Joint pain
• Nervousness
• Blurred vision
• Muscle pain
• Increased salivation

Serious

• Habit formation and physical dependence with prolonged use
• Suicidal thoughts or worsening mood changes
• Convulsions or seizures
• Abnormal bleeding
• Decreased urine output
• Fast heartbeat
• Uncontrolled body movements
• Reduced intellectual abilities

Warnings and precautions

• Stopping this medicine suddenly can cause serious withdrawal symptoms such as agitation, nausea, tremors, and sweating. The dose should always be reduced gradually under a doctor's supervision.
• This medicine is generally not recommended for people under 18 years old.
• This medicine can be habit-forming and may lead to physical dependence, especially with long-term use.
• This medicine may increase the risk of unusual bleeding or bruising, especially in people with bleeding disorders or those taking certain other medicines like aspirin or blood thinners.
• This medicine should be used with extra caution in people with a history of seizure disorders, since it may increase the risk of seizures happening again.
• This medicine is not recommended for people with closed-angle glaucoma, as it may make the condition worse.
• This medicine should be used carefully in people with respiratory disorders, as it may worsen their condition.
• This medicine is generally not recommended during pregnancy unless the doctor decides it is absolutely necessary, after weighing the risks and benefits.
• This medicine is generally not recommended while breastfeeding unless absolutely necessary, and the baby should be watched closely for any side effects if it is used.
• This medicine should be used carefully in people with kidney disease, since it may make their condition worse; kidney function should be monitored closely.
• The liver can be affected by this medicine. If you notice any unwanted effects, stop taking it and talk to your doctor before restarting.
• Avoid drinking alcohol while taking this medicine, since it greatly raises the risk of severe sleepiness, dizziness, and breathing problems.
• Do not drive or operate heavy machinery while taking this medicine, since it can affect your alertness and coordination.

Storage

• Store below 30° C
• Store Depran-10 Tablet in a cool and dry place
• Protect it from direct sunlight and moisture
• Keep the medicine out of reach of children
• Use the product before the expiry date mentioned on the packaging

When to see a doctor

• Get emergency medical help right away if you think you or someone else has taken too much of this medicine.
• Tell your doctor right away if you notice any unusual bleeding, bruising, or blood in the stool.
• Watch closely for any changes in mood or behavior, including thoughts of suicide, and report them to your doctor immediately.
• If you have a seizure or your seizures get worse while taking this medicine, treatment should be stopped and you should contact your doctor.

Alternatives

• Escitalopram alone
• Fluoxetine
• Sertraline