Safety
General information, not medical advice
Your prescriber and the leaflet in your pack know your situation. This page does not.
- Follow your prescriber and the leaflet
- Don't start, stop, or change a dose on your own
- Doses and warnings differ by country and product
Domstal Tablet: Uses, Dosage, Side Effects, Precautions and Alternates
| Generic name | Domperidone |
|---|---|
| Drug class | Anti-emetic (antiemetic) |
| Forms | Tablet |
Quick overview
Domstal Tablet contains domperidone, an anti-emetic medicine. It is used to prevent and manage nausea and vomiting, and to treat digestive issues caused by slow stomach emptying, such as bloating, indigestion, and post-meal discomfort. It works by blocking dopamine in the brain and by increasing movement in the stomach and intestines. Domstal is available as a tablet and should be used exactly as directed by a doctor.
What is Domstal Tablet
Domstal Tablet contains domperidone as its active ingredient. It is an antiemetic medication used to prevent and manage nausea and vomiting, and to treat digestive issues caused by slow stomach emptying, such as bloating, indigestion, and post-meal discomfort.
Domstal Tablet uses
- Control nausea, vomiting and motion sickness
- Treatment of gastroparesis (sluggish movements of the stomach)
- Treatment of chronic dyspepsia (indigestion)
- Nausea and vomiting
- Gastric motility disorders
- Post-surgical nausea
- Acid reflux and Gastroesophageal Reflux Disease (GERD)
- Indigestion and bloating
Benefits of Domstal Tablet
- Helps alleviate nausea and reduce vomiting by increasing stomach muscle contractions
- Improves gastric emptying, easing discomfort and promoting better digestion
- Helps food and food/acid pass more easily through the digestive tract
How Domstal Tablet works
Domstal blocks a brain chemical called dopamine that can trigger nausea and vomiting. It also increases the movement of the stomach and intestines, helping food pass through more quickly, which helps prevent nausea and vomiting.
Domstal Tablet dosage
Take exactly as directed by your doctor. Swallow the tablet whole with a glass of water on an empty stomach. For best results, take before food, about 30 minutes before a meal. Do not take with antacids like sodium bicarbonate; separate these by at least 1 to 2 hours.
If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed one and continue your normal schedule. Do not take a double dose to make up for a missed one.
Not recommended for use in children below 12 years of age and weighing less than 35 kg due to lack of safety data. Should be used with caution in elderly people, starting with the lowest possible dose.
| Age group | Dose |
|---|---|
| Under 12 Years | Use only if specifically prescribed by a doctor |
| 12–17 Years | 10 mg up to 3 times daily, depending on medical advice |
| Adults (18+ Years) | 10 mg up to 3 times daily; maximum 30 mg/day |
| Older Adults (65+ Years) | 10 mg up to 3 times daily only under medical supervision |
Available forms and strengths
Domstal Tablet is available as a tablet.
Side effects of Domstal Tablet
Common
- Dry mouth
- Drowsiness
- Headaches
- Fatigue
- Rashes
- Dizziness
- Stomach pain
- Diarrhoea
Serious
- Swelling of face, lips, eyelids, tongue, hands and feet
- Difficulty in breathing
- Irregular heartbeat
- Disrupted menstrual cycle
- Breast pain and tenderness
- Chest pain
- Fainting
- Extreme tiredness
Warnings and precautions
- Domstal should be avoided during pregnancy because there isn't enough safety information about it. Your doctor may still prescribe it if the benefits outweigh the risks.
- Do not take Domstal while breastfeeding. A small amount passes into breast milk and could cause side effects in the baby. It should only be used if your doctor considers it necessary.
- Use with extreme caution if you have kidney disease, since a diseased kidney cannot fully clear the medicine from the blood, raising the risk of toxicity.
- Use with extreme caution if you have liver disease, as this increases the risk of serious side effects and worsening your condition; your doctor may monitor liver function and adjust the dose.
- Do not drink alcohol while taking this medicine, as it increases side effects such as dizziness, drowsiness, difficulty concentrating, gastrointestinal bleeding, weakness, and fatigue.
- Be cautious about driving, since this medicine can cause sleepiness, confusion, or less control over your movements.
- Do not use if you are allergic to domperidone, have black or tarry stools or blood in stools, have liver, kidney, or heart disease, have a blockage or tear in the intestine, have a pituitary tumor called prolactinoma, or have low magnesium or high potassium levels.
- Not recommended if you have heart disease like congestive heart failure, since it can cause QT prolongation, affecting the heart's electrical activity and increasing the risk of worsening your condition.
- Should be used for the shortest duration possible and at the lowest effective dose; self-treatment without medical guidance is not advised.
- May interact with many other medicines and cause severe effects, including dangerous heart rhythm problems with certain antibiotics, antifungals, antidepressants, and heart medicines.
Storage
- Store it at room temperature and keep away from heat, moisture and light.
- Keep it away from children and pets.
When to see a doctor
- Get emergency medical help right away if you suspect an overdose, which can cause difficulty speaking, poor coordination, dizziness, fainting, irregular heartbeat, light-headedness, loss of balance, and poor muscle control.
- Talk to your doctor if you have heart disorders or liver or kidney problems, or if you experience palpitations, breathing issues, or loss of consciousness while taking this medicine.
- Seek immediate medical attention if you notice signs of an allergic reaction such as skin rash, itching or swelling of the face, tongue, or throat, dizziness, or breathing difficulty.
Alternatives
- Ondansetron
- Prochlorperazine
- Granisetron
Watch the video
FAQs
What is Domstal Tablet used for?
Domstal Tablet is used to control nausea, vomiting and motion sickness, and to treat gastroparesis, chronic dyspepsia, gastric motility disorders, post-surgical nausea, acid reflux/GERD, and indigestion and bloating.
How does Domstal Tablet work?
Domstal blocks a brain chemical called dopamine that can trigger nausea and vomiting, and it increases movement of the stomach and intestines, helping food pass through more quickly to prevent nausea and vomiting.
What is the dosage of Domstal Tablet?
For adults, the usual dose is 10 mg up to 3 times daily, with a maximum of 30 mg per day. It should be swallowed whole with water on an empty stomach, ideally 30 minutes before a meal, exactly as directed by a doctor.
What are the common side effects of Domstal Tablet?
Common side effects include dry mouth, drowsiness, headaches, fatigue, rashes, dizziness, stomach pain, and diarrhoea.
Can Domstal Tablet be taken during pregnancy or breastfeeding?
Domstal should be avoided during pregnancy due to insufficient safety information, and should not be taken while breastfeeding since a small amount passes into breast milk; it should only be used if the doctor considers it necessary.
General information, not medical advice
Your prescriber and the leaflet in your pack know your situation. This page does not.
- Follow your prescriber and the leaflet
- Don't start, stop, or change a dose on your own
- Doses and warnings differ by country and product
Sources
- Motilium 10mg Film-coated Tablets - Summary of Product Characteristics (SmPC) - (emc)
- CDSCO
- MOTILIUM® Tablets [Internet]. Janssen.com
- Drugs and Lactation Database (LactMed®) - Domperidone
- National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 3151, Domperidone
- Domperidone [Internet]. ScienceDirect Topics
- Domperidone 10mg Tablets - Summary of Product Characteristics (SmPC) - (emc)
- Medsafe.govt.nz Domperidone Consumer Medicine Information
Video
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