Espazine Tablet: Uses, Dosage, Side Effects, Precautions and Alternates

Quick overview

Espazine Tablet contains Trifluoperazine, a typical antipsychotic medicine used to treat schizophrenia and anxiety. It helps manage symptoms such as hallucinations, delusions, and feelings of worry or fear. Espazine works by blocking dopamine in the brain to help control mood and behavior. It is available as a tablet and as an injection.

What is Espazine Tablet

Espazine is a medicine containing Trifluoperazine, a typical antipsychotic. It is used to treat schizophrenia and anxiety, helping manage symptoms like hallucinations, delusions, and feelings of worry or fear.

Espazine Tablet uses

• Schizophrenia
• Anxiety
• Mental illness

Benefits of Espazine Tablet

• Helps improve mental clarity and stabilize mood
• Helps manage symptoms such as hallucinations, delusions, and feelings of worry or fear

How Espazine Tablet works

Trifluoperazine works by blocking dopamine, a brain chemical messenger that affects thoughts and mood, which helps control mood and behavior.

Espazine Tablet dosage

Espazine can be taken with or without food, but it is better to take it at a fixed time. Take it with food if it causes stomach upset. Taking it at bedtime may help avoid feeling sleepy during the day. Do not take in larger or smaller amounts than advised by your doctor. Do not stop using this medicine without consulting your doctor, and make sure to complete the full course of treatment. If a dose is missed, take it as soon as you remember, but skip it if it is almost time for your next dose; do not double up. This medicine is not recommended for use in children younger than 6 years old.

Available forms and strengths

• Tablet
• Injection

Side effects of Espazine Tablet

Common

• Constipation
• Stomach pain
• Dry mouth
• Headache
• Excessive sweating
• Agitation
• Drowsiness
• Fever
• Dizziness
• Confusion
• Sleeplessness
• Nausea
• Vomiting
• Weight gain
• Muscle rigidity
• Tremor
• Sudden lowering of blood pressure on standing
• Urinary retention
• Increased prolactin level in blood
• Abnormal voluntary movements

Serious

• Drowsiness or sleepiness
• Dizziness
• Dry mouth
• Constipation
• Blurred vision

Warnings and precautions

• This medicine should not be used by people with depression, tardive dyskinesia, irregular heartbeat, heart failure, Reye's syndrome, dementia, or liver disease unless a doctor advises it.
• Should not be used in people allergic to trifluoperazine or other phenothiazines, or those with severe central nervous system depression or coma.
• Should be used with extreme caution in people with seizure disorders, as it increases the risk of seizures recurring.
• Not recommended for people with dementia because it raises the risk of serious side effects, including death, especially in elderly patients.
• Should be used with extreme caution in people with a history of neuroleptic malignant syndrome, as it can worsen their condition.
• Should be used with extreme caution in people with a history of tardive dyskinesia, especially elderly women, due to increased risk of symptoms returning.
• This medicine interacts severely with certain drugs such as quinidine and codeine, and moderately with others like levodopa, cetirizine, and insulin aspart.
• Espazine can cause unwanted side effects in pregnant women and is not recommended unless absolutely necessary. 
• It may be unsafe for the developing baby based on animal studies, so talk to your doctor about the risks and benefits.
• Women who are breastfeeding may have serious side effects from this medicine, so it should only be used if absolutely necessary and under a doctor's guidance.
• This medicine should be used with extreme caution in people with kidney disease because it may worsen their condition; kidney function should be monitored closely.
• This medicine should be used with extreme caution in people with liver disease because it may worsen their condition; liver function should be monitored closely.
• Drinking alcohol while on this medicine is not recommended because it can cause severe harmful effects such as confusion, dizziness, nausea, vomiting, weakness, or fainting.
• It is not safe to drive or operate heavy machinery while taking this medicine because it can cause dizziness, blurred vision, confusion, or drowsiness.

Storage

• Store below 25°C.
• Keep away from heat, moisture, and direct sunlight.
• Keep in the original packaging.
• Keep out of reach of children.

When to see a doctor

• Get emergency medical help right away if you think you have taken too much of this medicine.
• Tell your doctor right away if you notice uncontrolled movements of the tongue, mouth, lips, jaw, hands, or feet.
• Report any unusual symptoms to your doctor right away if you have a seizure disorder.
• If you experience side effects during pregnancy, stop taking the medicine right away and consult your doctor before restarting it.

Alternatives

• Trifluoperazine
• Talecalm