Safety
General information, not medical advice
Your prescriber and the leaflet in your pack know your situation. This page does not.
- Follow your prescriber and the leaflet
- Don't start, stop, or change a dose on your own
- Doses and warnings differ by country and product
Omnacortil Tablet: Uses, Dosage, Side Effects, Precautions and Alternates
| Generic name | Prednisolone |
|---|---|
| Drug class | Corticosteroid (Glucocorticoid) |
| Forms | Tablet, Dispersible tablet, Oral drops, Oral solution/suspension, Syrup, Injection |
Quick overview
Omnacortil Tablet contains Prednisolone, a corticosteroid (glucocorticoid) medicine. It works like the natural hormone cortisol to calm an overactive immune system and reduce inflammation in the body. It is used for a range of inflammatory, autoimmune, respiratory, skin, joint, and other conditions, and is available in several forms and strengths. It should always be taken exactly as prescribed by a doctor.
What is Omnacortil Tablet
Omnacortil is a corticosteroid medicine that contains Prednisolone as its active ingredient. Prednisolone is a man-made version of cortisol, a hormone your body naturally makes. It helps calm an overactive immune system and reduce inflammation in the body.
Omnacortil Tablet uses
- Helps manage inflammation-related swelling, redness, and irritation
- Supports management of autoimmune conditions such as lupus under medical supervision
- Assists in relieving respiratory inflammation and allergy-related discomfort, including asthma and bronchitis
- Helps soothe inflammatory and allergic skin conditions like eczema and psoriasis
- Supports joint health by managing inflammation in conditions like rheumatoid arthritis and gouty arthritis
- Assists in managing inflammatory bowel conditions such as ulcerative colitis
- Used for eye disorders including keratitis
- Used for kidney disorders such as nephrotic syndrome
- Used for certain blood disorders
- Used to help prevent organ transplant rejection
- Used for severe allergic reactions and anaphylaxis
Benefits of Omnacortil Tablet
- Reduces inflammation and swelling
- Alleviates allergic reactions
- Suppresses an overactive immune response
- Helps manage autoimmune disorders
- May help improve breathing in asthma and related conditions
- Supports comfort and symptom control in joint inflammation
How Omnacortil Tablet works
Prednisolone works like the natural hormone cortisol made by your adrenal glands. It attaches to receptors inside cells and changes how certain genes work, which lowers the release of chemical substances that cause inflammation. This calms down an overactive immune system and reduces swelling, redness, and irritation in the body.
Omnacortil Tablet dosage
Take the tablet exactly as advised by the doctor, following the prescribed dose and duration. Swallow the tablet whole with a glass of water, or dissolve/disperse it in water if that form is prescribed. Do not crush, chew, or break the tablet unless instructed by your doctor.
It is generally recommended to take the medicine with or after food to help reduce stomach irritation. Try to take the tablet at the same time each day, and morning doses may work best to match the body's natural hormone patterns.
Do not change the dose or stop the medicine suddenly without medical guidance, as this can cause withdrawal symptoms and worsening of your condition. If you miss a dose, take it as soon as you remember; if it is almost time for your next dose, skip the missed one and continue your regular schedule. Never take two doses together to make up for a missed dose. Consult your doctor if multiple doses are missed or you are unsure about your schedule.
| Age group | Dose |
|---|---|
| Children | 0.1–2 mg/kg/day (dose depends on medical condition and doctor's advice) |
| Adults (18–64 Years) | 40 mg/day (adjusted according to condition and response) |
| Older Adults (65+ Years) | Lowest effective dose, commonly 5–40 mg/day depending on health condition |
Available forms and strengths
- Tablet
- Dispersible tablet
- Oral drops
- Oral solution/suspension
- Syrup
- Injection
Side effects of Omnacortil Tablet
Common
- Stomach discomfort or indigestion
- Increased appetite
- Mood-related changes
- Sleep disturbances
- Fluid retention or swelling
- Mild headache
- Increased sweating
- Temporary weight changes
- Restlessness or irritability
- Mild digestive discomfort
- Skin thinning
- Increased risk of infection
- Reduction in bone density
- Behavioural changes
- Increased blood glucose level
- Dizziness
- Fast heartbeat
- Aggression or anger
- Muscle pain
- Swelling in the hands or feet
Serious
- Severe allergic reactions or swelling
- Breathing difficulty or chest discomfort
- Severe stomach pain or persistent vomiting
- Vision changes or eye pain
- Unusual mood or behaviour changes
- Severe weakness or extreme tiredness
- Signs of infection such as fever or persistent sore throat
- Severe swelling of the face, hands, or feet
- Black or bloody stools
Warnings and precautions
- Do not use this medicine if you are allergic to prednisolone or any of its ingredients. Get medical help right away if you notice rash, itching, swelling, or breathing trouble.
- This medicine is not recommended if you have untreated severe or systemic fungal infections, active stomach ulcers or severe digestive bleeding, uncontrolled diabetes or severe high blood pressure without medical supervision, or severe osteoporosis or certain eye conditions unless your doctor advises otherwise.
- Do not stop taking this medicine suddenly, especially after long-term use, as this can cause unwanted effects and may require the dose to be lowered gradually.
- This medicine can lower your immune response, making infections more likely. Avoid close contact with people who have infections, and tell your doctor if you develop fever, sore throat, cough, or other unusual symptoms.
- Tell your doctor before receiving any vaccines while on this medicine, as it may reduce the effectiveness of vaccines, especially live vaccines, and increase infection risk.
- Long-term use in children may affect growth and development, so use in children should be strictly supervised by a doctor with careful monitoring of dose and duration.
- Avoid prolonged use of high doses in infants and children under 12, as it may increase pressure inside the skull and cause growth problems.
- Elderly patients should use this medicine under medical supervision, as they may be more sensitive to side effects such as bone weakness, high blood pressure, or blood sugar changes.
- Omnacortil should only be used during pregnancy if your doctor decides it is necessary, since long-term or high-dose use may affect the mother or unborn baby. Some sources say it may be unsafe or not recommended, so it should not be used without medical advice.
- Omnacortil may pass into breast milk in small amounts. It should only be used while breastfeeding under medical supervision, especially with prolonged treatment or higher doses.
- People with kidney problems should use Omnacortil carefully and under medical supervision, with regular monitoring, especially during long-term use.
- People with liver disorders should use Omnacortil carefully, since liver function can affect how the medicine works in the body. The dose may need to be adjusted.
- It is not clearly known how alcohol interacts with this medicine, but it is best to avoid alcohol or ask your doctor first, since alcohol may increase the risk of stomach irritation.
- Omnacortil is not usually known to affect driving ability, but if you feel dizzy, have blurred vision, or notice mood changes, avoid driving or using machinery until you feel well.
Storage
- Store Omnacortil Tablet at room temperature in a cool and dry place
- Store below 30°C
- Keep away from direct sunlight and moisture
- Keep the medicine in its original packaging until needed
- Keep out of the sight and reach of children and pets
When to see a doctor
- Stop the medicine and get medical help right away if you notice severe allergic reactions, breathing difficulty or chest discomfort, severe stomach pain or persistent vomiting, vision changes or eye pain, unusual mood or behavior changes, severe weakness, signs of infection like fever or sore throat, severe swelling of the face, hands, or feet, or black or bloody stools.
- Stop the medicine and seek help immediately if you get a rash, swelling of the face or lips, wheezing, or difficulty breathing.
- Get immediate medical help if you have vision problems, severe depression, confusion or seizures, irregular heartbeat, signs of infection, or suicidal thoughts.
- If you think you have taken too much of this medicine, contact your doctor right away, as an overdose can cause severe hormonal imbalances or other unwanted effects.
Alternatives
- Wysolone Tablet
- Methylprednisolone
- Deflazacort
Watch the video
FAQs
What is Omnacortil Tablet used for?
Omnacortil Tablet contains Prednisolone and is used to manage inflammation, autoimmune conditions like lupus, respiratory and allergic conditions such as asthma and bronchitis, skin conditions like eczema and psoriasis, joint conditions like rheumatoid and gouty arthritis, inflammatory bowel disease, certain eye and kidney disorders, blood disorders, organ transplant rejection, and severe allergic reactions.
How should I take Omnacortil Tablet?
Take it exactly as prescribed, swallowing the tablet whole with water or dissolving it if that form is prescribed. It is generally taken with or after food to reduce stomach irritation, at the same time each day, with morning doses often preferred to match the body's natural hormone pattern.
Can I stop taking Omnacortil Tablet suddenly?
No, you should not stop the medicine suddenly, especially after long-term use, as this can cause withdrawal symptoms and worsening of your condition. Any dose changes should be guided by your doctor.
What are the common side effects of Omnacortil Tablet?
Common side effects include stomach discomfort, increased appetite, mood changes, sleep disturbances, fluid retention, headache, increased sweating, weight changes, restlessness, skin thinning, increased infection risk, reduced bone density, and increased blood glucose levels.
Is Omnacortil Tablet safe during pregnancy and breastfeeding?
Omnacortil should only be used during pregnancy if the doctor decides it is necessary, as long-term or high-dose use may affect the mother or baby. It may also pass into breast milk in small amounts, so it should only be used while breastfeeding under medical supervision.
General information, not medical advice
Your prescriber and the leaflet in your pack know your situation. This page does not.
- Follow your prescriber and the leaflet
- Don't start, stop, or change a dose on your own
- Doses and warnings differ by country and product
Sources
- Yana Puckett, Preeti Patel, Abdullah A, Bokhari. Prednisolone. NIH National Library of Medicine, National centre for biotechnology information. StatPearls. [Revised in 26th April 2025].
- Alastair D Hay, Paul Little, Anthony Harnden, Matthew Thompson, Kay Wang, Denise Kendrick, Elizabeth Orton, Sara T Brookes, Grace J Young, Margaret May, Sandra Hollinghurst, Fran E Carroll, Harriet Downing, David Timmins, Natasher Lafond, Magdy El-Gohary, Michael Moore. Effect of Oral Prednisolone on Symptom Duration and Severity in Nonasthmatic Adults With Acute Lower Respiratory Tract Infection. NIH National Library of Medicine, National centre for biotechnology information. PubMed Central. [Revised in 22nd August 2017].
- Indian Pharmacopoeia
- CDSCO, manufacturer labeling
- National List of Essential Medicines (NLEM) 2022, Government of India.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
- Orapred ODT [Report]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021959lbl.pdf
- Prednisolone: uses, interactions, mechanism of action | DrugBank Online.
- Puckett, Y., Gabbar, A., & Bokhari, A. A. (2023, July 19). Prednisone. StatPearls - NCBI Bookshelf.
Video
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