Safety
General information, not medical advice
Your prescriber and the leaflet in your pack know your situation. This page does not.
- Follow your prescriber and the leaflet
- Don't start, stop, or change a dose on your own
- Doses and warnings differ by country and product
Zolfresh Tablet: Uses, Dosage, Side Effects, Precautions and Alternates
| Generic name | Zolpidem |
|---|---|
| Drug class | Non-benzodiazepine hypnotic (sedative-hypnotic) |
| Forms | Tablet, Controlled-release (CR) tablet |
Quick overview
Zolfresh Tablet contains Zolpidem, a non-benzodiazepine hypnotic used for the short-term treatment of insomnia. It helps people fall asleep faster, stay asleep longer, and enjoy better overall sleep quality. It works on brain receptors linked to a calming chemical called GABA. This medicine should be used exactly as prescribed, with attention to dosage, warnings, and precautions.
What is Zolfresh Tablet
Zolfresh Tablet contains Zolpidem, a prescription medicine used for the short-term treatment of insomnia (trouble sleeping). It belongs to a group of medicines called non-benzodiazepine hypnotics, which help people fall asleep faster and improve overall sleep quality.
Zolfresh Tablet uses
- Insomnia (trouble falling or staying asleep)
- Improvement of sleep onset
- Management of short-term sleep disturbances
- Support for restful sleep
Benefits of Zolfresh Tablet
- Reduces the time it takes to fall asleep
- Promotes deeper and more restful sleep throughout the night
- Helps maintain sleep and decreases frequent interruptions
- Better sleep may improve mood, focus, and emotional balance
How Zolfresh Tablet works
Zolpidem acts on specific receptors in the brain linked to a calming brain chemical called GABA. By boosting GABA's calming effect, it slows down brain activity and helps you relax, fall asleep faster, and stay asleep longer.
Zolfresh Tablet dosage
Take the tablet exactly as prescribed by your doctor. Swallow the tablet whole with a glass of water; do not crush or chew it. Take it shortly before bedtime, only when you can get a full night's sleep. Do not take an extra dose during the same night. Avoid taking it with or right after a heavy or high-fat meal, as this may delay how quickly it works. Do not stop the medicine suddenly without talking to your doctor, since this can cause withdrawal symptoms. Elderly patients and those with liver problems may need a lower dose. This medicine is not recommended for people under 18 years of age.
| Age group | Dose |
|---|---|
| Under 18 years | Not recommended |
| 18–60 years | 5–10 mg, once daily at bedtime |
| 60+ years | 5 mg, once daily at bedtime |
Available forms and strengths
- Tablet
- Controlled-release (CR) tablet
Side effects of Zolfresh Tablet
Common
- Dizziness
- Drowsiness/sleepiness
- Headache
- Nausea
- Stomach pain or discomfort
- Vomiting
- Memory problems
- Vertigo
- Back pain
- Double vision
- Dry mouth
- Loss of appetite
- Unsteadiness
- Confusion
- Fast heartbeat
- Blurred vision
Serious
- Complex sleep behaviors like sleepwalking or sleep-driving (driving while not fully awake, with no memory of it)
- Hallucinations
- Depression or suicidal thoughts
- Severe allergic reactions (anaphylaxis, angioedema)
- Hepatitis (liver inflammation)
Warnings and precautions
- Zolfresh should only be used in pregnancy if clearly necessary and prescribed by a doctor, since it can cause unwanted effects. Tell your doctor if you are pregnant or planning to become pregnant.
- Small amounts of zolpidem can pass into breast milk. Talk to your doctor before using this medicine while breastfeeding, and watch your baby for unusual sleepiness or feeding changes.
- People with kidney problems should tell their doctor before taking this medicine, as medical supervision may be needed, although no dose change is usually required.
- People with liver problems may need a lower dose and closer monitoring. This medicine should not be used in people with severe liver impairment.
- Do not drink alcohol while taking this medicine, since alcohol can greatly increase drowsiness, dizziness, poor coordination, and the risk of serious side effects.
- This medicine can cause drowsiness, reduced alertness, poor concentration, and slower reaction times. Do not drive or operate machinery after taking it.
- Do not stop taking this medicine suddenly, as it may cause withdrawal symptoms like seizures, behavioral changes, tremors, and anxiety. Any dose reduction should be done gradually under a doctor's guidance.
- This medicine can increase the risk of suicidal thoughts. Watch for any changes in mood or behavior and tell your doctor right away if these occur.
- This medicine can be habit-forming, especially with prolonged use or high doses. People with a history of alcohol or drug abuse should use it carefully, and any stopping of treatment should be done gradually.
- This medicine is not recommended for people under 18 years old, since its safety and effectiveness have not been established in this age group.
- Do not take this medicine with or right after a heavy or high-fat meal, as it may delay how quickly you fall asleep.
- This medicine should not be used by people with severe liver impairment, as it can worsen their condition.
- This medicine should not be used by people with a known allergy to zolpidem or to myasthenia gravis, due to higher risk of serious side effects.
- This medicine should not be taken with certain other drugs, including chloramphenicol, codeine, and tramadol, due to the risk of severe side effects.
- Taking this medicine together with ritonavir can be potentially fatal, increasing the risk of prolonged sedation and slowed or stopped breathing.
- This medicine may cause complex sleep behaviors such as sleepwalking or driving while not fully awake, with no memory of the event afterward.
Storage
- Store below 25°C.
- Keep in a cool and dry place.
- Protect from direct sunlight and moisture.
- Keep the tablets in their original packaging.
- Keep out of reach of children and pets.
- Do not use after the expiry date.
- Dispose of unused medicine responsibly as advised by a pharmacist.
When to see a doctor
- Get emergency medical help right away if you think you have taken too much of this medicine.
- Contact your doctor immediately if you notice unusual sleep behaviors, such as sleepwalking, sleep-driving, or doing activities while not fully awake.
- Tell your doctor right away if you notice any changes in mood, new or worsening depression, or thoughts of suicide while taking this medicine.
- Seek medical help immediately if you experience signs of a severe allergic reaction, such as swelling or difficulty breathing.
- If your insomnia does not improve after 7 to 10 days of treatment, contact your doctor, as this may be a sign of an underlying medical or psychiatric condition.
Alternatives
- Stilnoct
- Zolpid
- Zolpirest
Watch the video
FAQs
What is Zolfresh Tablet used for?
Zolfresh Tablet, containing Zolpidem, is used for the short-term treatment of insomnia, helping people fall asleep faster, stay asleep longer, and improve overall sleep quality.
How should Zolfresh Tablet be taken?
It should be swallowed whole with water shortly before bedtime, only when a full night's sleep is possible. It should not be crushed, chewed, or taken with or right after a heavy or high-fat meal, and no extra dose should be taken the same night.
What is the recommended dosage of Zolfresh Tablet?
Adults aged 18–60 years typically take 5–10 mg once daily at bedtime, while those over 60 years take 5 mg once daily. It is not recommended for people under 18 years of age.
What are the serious side effects of Zolfresh Tablet?
Serious side effects include complex sleep behaviors like sleepwalking or sleep-driving, hallucinations, depression or suicidal thoughts, severe allergic reactions, and hepatitis.
Can I drink alcohol while taking Zolfresh Tablet?
No, alcohol should be avoided while taking this medicine as it can greatly increase drowsiness, dizziness, poor coordination, and the risk of serious side effects.
General information, not medical advice
Your prescriber and the leaflet in your pack know your situation. This page does not.
- Follow your prescriber and the leaflet
- Don't start, stop, or change a dose on your own
- Doses and warnings differ by country and product
Sources
- US Food and Drug Administration (FDA). Package leaflet information for the user; Ambien® (zolpidem tartrate)
- KD Tripathi. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 406-407
- April Hazard Vallerand, Cynthia A. Sanoski. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1296-1298
- U.S. Food and Drug Administration (FDA). Ambien (Zolpidem Tartrate) Prescribing Information.
- Mayo Clinic. Zolpidem (Oral Route): Uses, Dosage and Precautions.
- MedlinePlus. Zolpidem Drug Information.
- National Health Service (NHS). Zolpidem: Uses, Side Effects and Safety Information.
- Cleveland Clinic. Zolpidem Tablets: Uses and Side Effects.
- National Sleep Foundation. Understanding Insomnia and Sleep Disorders.
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